Second Mitochondria-Derived Activator of Caspase (DIABLO) Peptide
DIABLO
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975791
Quick Overview for Second Mitochondria-Derived Activator of Caspase (DIABLO) Peptide (ABIN975791)
Target
DIABLO
(Second Mitochondria-Derived Activator of Caspase (DIABLO))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DIABLO antibody (Catalog #: AVARP02023_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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Background
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DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
Alias Symbols: SMAC, SMAC3, DFNA64, DIABLO-S
Protein Interaction Partner: BIRC6,BIRC6,LTBR,NGFRAP1,XIAP,XIAP,BIRC2,BIRC3,BIRC5,BIRC6,BIRC7,CASP9,DIABLO,HTRA2,LTBR,NGFRAP1,XIAP,BIRC2,BIRC3,BIRC5,DIABLO,LTBR,NAIP,TNFSF14,USP13,XIAP
Protein Size: 186 -
Molecular Weight
- 21 kDa
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Gene ID
- 56616
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NCBI Accession
- NM_138930, NP_620308
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UniProt
- Q502X2
Target
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